Chloro-N,N-diethylacetamide → HCID 90313740, compound

HRID 1524059Notes

Reaction equation

HRID 1524059 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8](CC(N)=O)(=[O:10])=[O:9].Cl[CH2:16][C:17]([N:19]([CH2:22][CH3:23])[CH2:20][CH3:21])=[O:18]>>[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8]([CH2:16][C:17]([N:19]([CH2:22][CH3:23])[CH2:20][CH3:21])=[O:18])(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 16844Chloro-N,N-diethylacetamideHCID 47218127HCID 47218127, compound

Product 1

HCID 90313740HCID 90313740, compound

Procedure

The title compound was prepared in a manner similar to that described for 2-((2-bromophenyl)sulfonyl)acetamide using 2-chloro-N,N-diethylacetamide in Step A. 1H NMR (600 MHz, DMSO-d6) δ 8.01-7.97 (m, 1H), 7.91-7.87 (m, 1H), 7.66-7.60 (m, 2H), 4.75 (s, 2H), 3.47-3.39 (q, J=7.1, 2H), 3.25-3.14 (q, J=7.0, 2H), 1.18-1.09 (t, J=7.1, 3H), 0.99-0.87 (t, J=7.0, 3H).

Sources & evidence

ORD record
ord-1e230724d46f4f85b3d5cc58e339f507
Source dataset
uspto-grants-2015_07
Patent number
US09079866B2

Reaction notes

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