HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 60727074, compound → HCID 90313956, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 60727074 | HCID 60727074 | — |
| Reactant | 5-(2-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrimidin-2-amine | HCID 90313142 | — |
| Product | HCID 90313956 | HCID 90313956 | — |
Reaction Steps
The title compound was prepared in a manner similar to that described in Example 88 using 2-(2-bromophenoxy)-4-(trifluoromethyl)pyrimidine and 5-(2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyrimidin-2-amine. MS (ESI): mass calcd. for C21H13F4N5O, 427.11; m/z found, 428.0 [M+H]+. 1H NMR (400 MHz, DMSO-d6) δ 8.93 (d, J=4.9, 1H), 8.41 (d, J=1.4, 2H), 7.69 (d, J=4.9, 1H), 7.60-7.57 (m, 1H), 7.55-7.50 (m, 2H), 7.46-7.38 (m, 2H), 7.35-7.29 (m, 2H), 6.88 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079866B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-04a4a4c06c504a8696ee7a1369760970 |
| Source note | uspto-grants-2015_07 |