HCID 68044582, compound → HCID 68044639, compound

Participants

Reaction Steps

To the material from Step 6 (31 mg, 0.044 mmol) and 10% palladium on carbon (5 mg, 0.004 mmol) was added ethyl acetate (0.5 mL). The reaction mixture was purged with nitrogen, and stirred under hydrogen (1 atm) overnight. Upon addition of DCM, the reaction mixture was filtered through celite, washed with dichloromethane, and the filtrate was concentrated in vacuo. The residue was purified by column chromatography on silica gel using ethyl acetate-hexanes (0:100 to 90:10) to afford 23 mg of the title compound as a colorless foam. LCMS (M+1)=671.

Provenance & Evidence