3-Cyanophenylboronic acid → HCID 71259691, compound

Participants

Reaction Steps

The title compound was prepared in an analogous manner to that described in Example 28 using (3-cyanophenyl)boronic acid and 3-bromo-N-(2,4-dimethoxybenzyl)-1-methyl-N-(1,2,4-thiadiazol-5-yl)-1H-indole-6-sulfonamide, and the desired product, 3-(3-cyanophenyl)-1-methyl-N-(1,2,4-thiadiazol-5-yl)-1H-indole-6-sulfonamide, was isolated as an off-white solid. 1H NMR (500 MHz, DMSO-d6) δ ppm 3.90 (s, 3 H) 7.56 (dd, J=8.48, 1.60 Hz, 1 H) 7.61-7.69 (m, 2 H) 7.86-7.92 (m, 2 H) 7.94-8.07 (m, 4 H). m/z (ESI) 395.1 (M+H)+.

Provenance & Evidence