Phenylboronic Acid → HCID 71259526, compound

Participants

Reaction Steps

The title compound was prepared in an analogous manner to that described in Example 28 using phenylboronic acid and 3-bromo-N-(2,4-dimethoxybenzyl)-1-methyl-N-(1,2,4-thiadiazol-5-yl)-1H-indole-6-sulfonamide, and the desired product, 1-methyl-3-phenyl-N-(1,2,4-thiadiazol-5-yl)-1H-indole-6-sulfonamide, was isolated as an off-white solid. 1H NMR (500 MHz, DMSO-d6) δ ppm 3.88 (s, 3 H) 7.15-7.30 (m, 1 H) 7.43 (t, J=7.73 Hz, 2 H) 7.48-7.55 (m, 1 H) 7.61-7.68 (m, 2 H) 7.81 (d, J=4.47 Hz, 2 H) 7.85-7.89 (m, 2 H). m/z (ESI) 370.1 (M+H)+.

Provenance & Evidence