HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichloro-5-fluoropyrimidine → 2,5-Dichloro-4-methylpyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichloro-5-fluoropyrimidine | HCID 250705 | — |
| Reactant | 2-Chloro-5-fluoro-4-methylpyrimidine | HCID 20778073 | — |
| Product | 2,5-Dichloro-4-methylpyrimidine | HCID 21278621 | — |
Reaction Steps
The title compound was prepared in a manner analogous to Intermediate 55, substituting 2,4,5-trichloropyrimidine for 2,4-dichloro-5-fluoropyrimidine. 1H NMR (500 MHz, CDCl3): 8.47 (s, 1H), 2.61 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079911B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-f4f2aa542047402bae706e39a23f53fe |
| Source note | uspto-grants-2015_07 |