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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1524970Generated: October 26, 2026

2-(Thiophen-2-yl)benzoic acid → 2-(4-Phenylpyrimidin-2-yl)-5-[(2-thiophen-2-ylphenyl)carbonyl]octahydro-pyrrolo[3,4-c]pyrrole

https://huagongshe.com/reaction/1524970

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Thiophen-2-yl)benzoic acidHCID 5105623—
Reactant2-(4-Phenyl-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrroleHCID 69939098—
Product2-(4-Phenylpyrimidin-2-yl)-5-[(2-thiophen-2-ylphenyl)carbonyl]octahydro-pyrrolo[3,4-c]pyrroleHCID 52916848—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 26 and 2-thiophen-2-yl-benzoic acid. MS (ESI) mass calcd. for C27H24N4OS, 452.58; m/z found, 453.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079911B2
Source datasetuspto-grants-2015_07
ORD IDord-0dbc04d1b285469ca216809db1b37a45
Source noteuspto-grants-2015_07