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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1524977Generated: October 26, 2026

2-(3-fluorophenyl)benzoic Acid → 2-{5-[(3'-Fluorobiphenyl-2-yl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxaline

https://huagongshe.com/reaction/1524977

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-fluorophenyl)benzoic AcidHCID 2782684—
Reactant2-(Hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-quinoxalineHCID 61037281—
Product2-{5-[(3'-Fluorobiphenyl-2-yl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}quinoxalineHCID 52917008—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 35 and 3′-fluoro-biphenyl-2-carboxylic acid. MS (ESI) mass calcd. for C27H23FN4O, 438.51; m/z found, 439.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079911B2
Source datasetuspto-grants-2015_07
ORD IDord-7150bb35e4aa4f98a1777e24fa1c2957
Source noteuspto-grants-2015_07