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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1525039Generated: October 25, 2026

2-Chloro-4-methylquinoline → 2-{5-[(2,4-Dimethoxyphenyl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-4-methylquinoline

https://huagongshe.com/reaction/1525039

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-4-methylquinolineHCID 69449—
Reactant(2,4-Dimethoxy-phenyl)-(hexahydro-pyrrolo[3,4-c]pyrrol-2-yl)-methanoneHCID 66211208—
Product2-{5-[(2,4-Dimethoxyphenyl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-4-methylquinolineHCID 67116456—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 38 and 2-chloro-4-methyl-quinoline. MS (ESI) mass calcd. for C25H27N3O3, 417.51; m/z found, 418.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079911B2
Source datasetuspto-grants-2015_07
ORD IDord-1437846e847f49159768a5f7f0568c6e
Source noteuspto-grants-2015_07