HRID1525060

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：O=C(O)c1ccccc1-c1ccc(C(F)(F)F)cc1

HCID55251

Xenalipin

C14H9F3O2

反应SMILES：c1ccc(-c2ccnc(N3CC4CNCC4C3)n2)cc1

HCID69939098

未命名化合物

PRODUCTS

产物

反应SMILES：O=C(c1ccccc1-c1ccc(C(F)(F)F)cc1)N1CC2CN(c3nccc(-c4ccccc4)n3)CC2C1

HCID67117173

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 26 and 4′-trifluoromethyl-biphenyl-2-carboxylic acid. MS (ESI): mass calculated for C30H53F3N4O, 514.56; m/z found 515.3 [M+H]+.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-f4fc1ff4504342f6859fbcfe7f9c80f3
来源数据集: uspto-grants-2015_07
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US09079911B2
来源说明: uspto-grants-2015_07

反应SMILES

[C:1]1([C:7]2[CH:12]=[CH:11][N:10]=[C:9]([N:13]3[CH2:20][CH:19]4[CH:15]([CH2:16][NH:17][CH2:18]4)[CH2:14]3)[N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[F:21][C:22]([F:39])([F:38])[C:23]1[CH:28]=[CH:27][C:26]([C:29]2[C:30]([C:35](O)=[O:36])=[CH:31][CH:32]=[CH:33][CH:34]=2)=[CH:25][CH:24]=1>>[C:1]1([C:7]2[CH:12]=[CH:11][N:10]=[C:9]([N:13]3[CH2:14][CH:15]4[CH2:16][N:17]([C:35]([C:30]5[CH:31]=[CH:32][CH:33]=[CH:34][C:29]=5[C:26]5[CH:27]=[CH:28][C:23]([C:22]([F:21])([F:38])[F:39])=[CH:24][CH:25]=5)=[O:36])[CH2:18][CH:19]4[CH2:20]3)[N:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1