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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1525065Generated: November 3, 2026

3-phenylpyridine-2-carboxylic Acid → [5-(4,6-Dimethoxy-pyrimidin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-(3-phenyl-pyridin-2-yl)-methanone

https://huagongshe.com/reaction/1525065

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-phenylpyridine-2-carboxylic AcidHCID 2762789—
Reactant2-(4,6-Dimethoxy-pyrimidin-2-yl)-octahydro-pyrrolo[3,4-c]pyrroleHCID 67116491—
Product[5-(4,6-Dimethoxy-pyrimidin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-(3-phenyl-pyridin-2-yl)-methanoneHCID 69938950—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 39 and 3-phenyl-pyridine-2-carboxylic acid. MS (ESI): mass calculated for C24H25N5O3, 431.50; m/z found 432.3 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079911B2
Source datasetuspto-grants-2015_07
ORD IDord-ee407311d59d479f9fce8f3a9cd14609
Source noteuspto-grants-2015_07