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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1525066Generated: October 26, 2026

2-(3,6-Dimethyl-pyrazin-2-yl)-octahydro-pyrrolo[3,4-c]pyrrole → [5-(3,6-Dimethyl-pyrazin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-(5-fluoro-2-pyrimidin-2-yl-phenyl)-methanone

https://huagongshe.com/reaction/1525066

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3,6-Dimethyl-pyrazin-2-yl)-octahydro-pyrrolo[3,4-c]pyrroleHCID 66210482—
Reactant5-Fluoro-2-(pyrimidin-2-yl)benzoic acidHCID 67086950—
Product[5-(3,6-Dimethyl-pyrazin-2-yl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-(5-fluoro-2-pyrimidin-2-yl-phenyl)-methanoneHCID 67116382—

Reaction Steps

The title compound was prepared in a manner analogous to Example 15 utilizing Intermediate 34 and Intermediate 13. MS MS (ESI): mass calculated for C23H23FN6O, 418.47; m/z found 419.2 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09079911B2
Source datasetuspto-grants-2015_07
ORD IDord-56fe3b00e3ee4bc5b48b6cbbe7232bf3
Source noteuspto-grants-2015_07