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HRID1525068

反应详情

EQUATION

反应方程式

HRID 1525068 的结构方程式

REACTANTS

反应物

4
结构：Cc1cc(C)nc(Cl)n1
HCID20550

Pyrimidine, 2-chloro-4,6-dimethyl-

C6H7ClN2

结构：Cc1cc(Cl)nc(C)n1
HCID3154199

4-chloro-2,6-dimethylpyrimidine

C6H7ClN2

结构：CC(C)(C)OC(=O)N1CC2CNCC2C1
HCID4142526

tert-Butyl hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

C11H20N2O2

结构：O=C(c1cc(F)ccc1-n1nccn1)N1CC2CNCC2C1
HCID67116387

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(N2CC3CN(C(=O)c4cc(F)ccc4-n4nccn4)CC3C2)nc(C)n1
HCID67116226

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(=O)O
溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

The title compound was prepared in a manner analogous to Intermediate 23, substituting (5-fluoro-2-(2H-1,2,3-triazol-2-yl)phenyl)(hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)methanone (Intermediate 21) for hexahydro-pyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester and 4-chloro-2,6-dimethylpyrimidine for 2-chloro-4,6-dimethyl-pyrimidine in Step A. MS (ESI) mass calcd for C21H22FN7O, 407.19; m/z found, 408.2 [M+H]+.