HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Boc-3-aminopyrrolidine → HCID 89561391, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Boc-3-aminopyrrolidine | HCID 2756370 | — |
| Reactant | HCID 87949867 | HCID 87949867 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 89561391 | HCID 89561391 | 68% |
Reaction Steps
The title compound was prepared in analogy to Example 17, step 17.1, starting from [(2R)-oxiranylmethyl]-carbamic acid benzyl ester (8.23 g; prepared according to WO 2004/002973) and rac-3-amino-1-Boc-pyrrolidine (7.40 g; commercial) in MeCN (300 mL), affording a colourless oil (10.7 g; 68% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079922B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-4fba7eaff96f4227bd196fe8bce2f468 |
| Source note | uspto-grants-2015_07 |