HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Cyanopyridine-2-carboxylic acid → HCID 71059646, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Cyanopyridine-2-carboxylic acid | HCID 12400734 | — |
| Reactant | HCID 86674113 | HCID 86674113 | — |
| Product | HCID 71059646 | HCID 71059646 | 74% |
Reaction Steps
The condensation of (R)-5′,5′-difluoro-5′,6′-dihydrospiro[chroman-4,4′-[1,3]oxazine]-2′,6-diamine (intermediate B7.1) and 5-cyanopicolinic acid yielded the title compound (74% yield) as a yellow solid. MS (ISP): m/z=400.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09079919B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-6733e1b120fc4e30b56fdd9edbb19c5a |
| Source note | uspto-grants-2015_07 |