HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1525776Generated: October 26, 2026
3-chloro-1-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid → 3-(3-chloro-1H-pyrazol-1-yl)pyridine
https://huagongshe.com/reaction/1525776
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-chloro-1-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid | HCID 86705825 | — |
| Catalyst | HCID 178419072 | HCID 178419072 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | 3-(3-chloro-1H-pyrazol-1-yl)pyridine | HCID 67499540 | — |
Reaction Steps
In another embodiment, 3-chloro-1-(pyridin-3-yl)-1H-pyrazole-4-carboxylic acid (4) and copper(I) oxide are mixed with N,N-dimethylacetamide and heated to about 125° C. The 3-(3-chloro-1H-pyrazol-1-yl)pyridine (5b) can be isolated and purified by standard techniques.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09085552B1 |
|---|
| Source dataset | uspto-grants-2015_07 |
|---|
| ORD ID | ord-b1dd1d264e5d49df85e1c715a330bbc1 |
|---|
| Source note | uspto-grants-2015_07 |
|---|
