Potassium Carbonate → HCID 71270812, compound

Participants

Reaction Steps

A solution of the crude 9-(1-(4-bromophenyl)-2-oxopropyl)-4-cyclopropyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one from Example 24b in 1,4-dioxane (1.5 mL) was treated with 7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline (0.245 mmol), PdCl2(dppf)-CH2Cl2 adduct (0.0113 mmol), and 2M aq potassium carbonate (0.668 mmol). The reaction vessel was purged with nitrogen and sealed, and the mixture irradiated in a Biotage

Provenance & Evidence