反应详情

600 mg (3.35 mmol) of the compound from Example 39A are heated in 1.7 ml (10.0 mmol) dimethylformamide diethyl acetal overnight at 100° C. After cooling, the mixture is concentrated and the residue is purified by means of preparative HPLC (RP18 column; mobile phase: acetonitrile/water gradient).

1. temperatureAfter cooling
2. concentrationthe mixture is concentrated
3. customthe residue is purified by means of preparative HPLC (RP18 column; mobile phase: acetonitrile/water gradient)