Ethanol → HCID 117666925, compound

Participants

Reaction Steps

To a mixture of 1-methyl-9-(4-nitrophenyl)-1,9-diazaspiro[5.5]undecane (680 mg), ethanol (10 mL), and tetrahydrofuran (10 mL) was added 10% palladium-supported carbon (50% wet product) (150 mg), followed by stirring for 5 hours under a hydrogen gas atmosphere (1 atm). The reaction mixture was filtered through celite and then the solvent was evaporated under reduced pressure to obtain 4-(1-methyl-1,9-diazaspiro[5.5]undec-9-yl)aniline (0.6 g) as a pale purple solid.

Provenance & Evidence