HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 117666940, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | p-Fluoronitrobenzene | HCID 9590 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1-(Oxan-4-yl)piperazine--hydrogen chloride (1/2) | HCID 44120481 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 117666940 | HCID 117666940 | — |
Reaction Steps
A mixture of 1-fluoro-4-nitrobenzene (750 μL), 1-(tetrahydro-2H-pyran-4-yl)piperazine dihydrochloride (2.1 g), potassium carbonate (3.2 g), and N,N-dimethylformamide (10 mL) was stirred at room temperature for 3 days. To the reactant was added water, and the precipitated solid was collected by filtration and then dried under reduced pressure to obtain 1-(4-nitrophenyl)-4-(tetrahydro-2H-pyran-4-yl)piperazine (1.83 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09085540B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-85c579c3ec894ddc9759756dc48bc552 |
| Source note | uspto-grants-2015_07 |