2-Chloroaniline → HCID 117770203, compound

Participants

Reaction Conditions

Reaction Steps

To a mixture of 4-hydroxy-6-methyl-2H-pyran-2-one (10.0 g) and 1,2-dichlorobenzene (9.91 mL) was added 2-chloroaniline (10.1 g) over 10 min at 165° C., and the reaction mixture was stirred at 165° C. for 30 min, and cooled to room temperature. The resulting solid was collected by filtration, and washed with dichloromethane to give the title compound (5.19 g).

Provenance & Evidence