6-Methoxy-1H-indole-3-carboxylic acid → 3-Isocyanato-6-methoxy-indole-1-carboxylic acid amide

HRID 1527158Notes

Reaction equation

HRID 1527158 reaction equation
[CH3:1][O:2]C1C=C2C(C(C(O)=O)=CN2)=CC=1.[N:15]([C:18]1[C:26]2[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=2)[N:20]([C:27]([NH2:29])=[O:28])[CH:19]=1)=[C:16]=[O:17]>>[N:15]([C:18]1[C:26]2[C:21](=[CH:22][C:23]([O:2][CH3:1])=[CH:24][CH:25]=2)[N:20]([C:27]([NH2:29])=[O:28])[CH:19]=1)=[C:16]=[O:17]

Participants

3

Reactant 2

HCID 177509566-Methoxy-1H-indole-3-carboxylic acidHCID 575200853-Isocyanato-indole-1-carboxylic acid amide

Product 1

HCID 866737883-Isocyanato-6-methoxy-indole-1-carboxylic acid amide

Procedure

was prepared from 6-methoxy-indole-3-carboxylic acid using the protocol described for the preparation of 3-isocyanato-indole-1-carboxylic acid amide scheme A1.

Sources & evidence

ORD record
ord-4ab3a084845f4288b97cbad109eba2a6
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

Loading…