6-Chloroindole → 6-Chloro-3-isocyanato-indole-1-carboxylic acid amide

HRID 1527174Notes

Reaction equation

HRID 1527174 reaction equation
[Cl:1]C1C=C2C(C=CN2)=CC=1.C(O[C:15]1[CH:16]=[C:17]2[C:21](=[CH:22][CH:23]=1)[N:20]([C:24]([NH2:26])=[O:25])[CH:19]=[C:18]2[N:27]=[C:28]=[O:29])C=C>>[Cl:1][C:23]1[CH:22]=[C:21]2[C:17]([C:18]([N:27]=[C:28]=[O:29])=[CH:19][N:20]2[C:24]([NH2:26])=[O:25])=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 871116-ChloroindoleHCID 866737945-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide

Product 1

HCID 866737976-Chloro-3-isocyanato-indole-1-carboxylic acid amide

Procedure

was prepared from 6-chloroindole using the protocol described for steps B-E in scheme A4 for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide.

Sources & evidence

ORD record
ord-30add015e0434c7d9aad94c82efde421
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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