HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(Trifluoromethyl)indole → 6-Trifluoromethyl-3-isocyanato-indole-1-carboxylic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(Trifluoromethyl)indole | HCID 2777523 | — |
| Reactant | 5-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide | HCID 86673794 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | 6-Trifluoromethyl-3-isocyanato-indole-1-carboxylic acid amide | HCID 86673798 | — |
Reaction Steps
was prepared from 6-trifluoromethylindole using the protocol described for steps B-E in scheme A4 for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide except that the acyl azide intermediate was prepared in 1,2 dimethoxyethane instead of toluene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09085555B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-da31a75e68e547be9f7a73732b1b48e4 |
| Source note | uspto-grants-2015_07 |