5-fluoro-1H-indole-3-carbaldehyde → 5-Fluoro-3-isocyanato-indole-1-carboxylic acid amide

HRID 1527176Notes

Reaction equation

HRID 1527176 reaction equation
[F:1]C1C=C2C(=CC=1)NC=C2C=O.C(O[C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[N:22]([C:26]([NH2:28])=[O:27])[CH:21]=[C:20]2[N:29]=[C:30]=[O:31])C=C>>[F:1][C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[N:22]([C:26]([NH2:28])=[O:27])[CH:21]=[C:20]2[N:29]=[C:30]=[O:31]

Participants

3

Reactant 2

HCID 2590895-fluoro-1H-indole-3-carbaldehydeHCID 866737945-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide

Product 1

HCID 866737995-Fluoro-3-isocyanato-indole-1-carboxylic acid amide

Procedure

was prepared from 5-fluoro-1H-indole-3-carbaldehyde using the protocol described for steps C, D and E in scheme A4 for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide.

Sources & evidence

ORD record
ord-500aed0264ec4bf8b004f1e7b1b9a96f
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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