6-Fluoroindole-3-carboxaldehyde → 6-Fluoro-3-isocyanato-indole-1-carboxylic acid amide

HRID 1527177Notes

Reaction equation

HRID 1527177 reaction equation
[F:1]C1C=C2C(C(C=O)=CN2)=CC=1.C(O[C:17]1[CH:18]=[C:19]2[C:23](=[CH:24][CH:25]=1)[N:22]([C:26]([NH2:28])=[O:27])[CH:21]=[C:20]2[N:29]=[C:30]=[O:31])C=C>>[F:1][C:25]1[CH:24]=[C:23]2[C:19]([C:20]([N:29]=[C:30]=[O:31])=[CH:21][N:22]2[C:26]([NH2:28])=[O:27])=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 2629036-Fluoroindole-3-carboxaldehydeHCID 866737945-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide

Product 1

HCID 866738006-Fluoro-3-isocyanato-indole-1-carboxylic acid amide

Procedure

was prepared from 6-fluoro-1H-indole-3-carbaldehyde [2795-41-7] using the protocol described for steps C, D and E in scheme A4 for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide.

Sources & evidence

ORD record
ord-2fe29f08e11a4f709067e298e66aa17d
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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