5-Methoxyindole-3-carbaldehyde → 3-Isocyanato-5-methoxy-indole-1-carboxylic acid amide

HRID 1527178Notes

Reaction equation

HRID 1527178 reaction equation
COC1C=C2C(=CC=1)NC=C2C=O.[CH2:14]([O:17][C:18]1[CH:19]=[C:20]2[C:24](=[CH:25][CH:26]=1)[N:23]([C:27]([NH2:29])=[O:28])[CH:22]=[C:21]2[N:30]=[C:31]=[O:32])C=C>>[N:30]([C:21]1[C:20]2[C:24](=[CH:25][CH:26]=[C:18]([O:17][CH3:14])[CH:19]=2)[N:23]([C:27]([NH2:29])=[O:28])[CH:22]=1)=[C:31]=[O:32]

Participants

3

Reactant 2

HCID 827585-Methoxyindole-3-carbaldehydeHCID 866737945-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide

Product 1

HCID 866738013-Isocyanato-5-methoxy-indole-1-carboxylic acid amide

Procedure

was prepared from 5-methoxy-1H-indole-3-carbaldehyde using the protocol described for steps C, D and E in scheme A4 for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide.

Sources & evidence

ORD record
ord-6020fb3439fd4431ab818806ce1868b3
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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