6-(Difluoromethoxy)-1H-indole → HCID 86673803, compound

HRID 1527180Notes

Reaction equation

HRID 1527180 reaction equation
[F:1][CH:2]([F:13])[O:3]C1C=C2C(C=CN2)=CC=1.C(O[C:18]1[CH:19]=[C:20]2[C:24](=[CH:25][CH:26]=1)[N:23]([C:27]([NH2:29])=[O:28])[CH:22]=[C:21]2[N:30]=[C:31]=[O:32])C=C>>[F:1][CH:2]([F:13])[O:3][C:26]1[CH:25]=[C:24]2[C:20]([C:21]([N:30]=[C:31]=[O:32])=[CH:22][N:23]2[C:27]([NH2:29])=[O:28])=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 538446306-(Difluoromethoxy)-1H-indoleHCID 866737945-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide

Product 1

HCID 86673803HCID 86673803, compound

Procedure

was prepared from 6-difluoromethoxy-1H-indole [200207-21-2] using the protocol described for steps B-E in Scheme A4 for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide.

Sources & evidence

ORD record
ord-5ea30769ddeb4feb9c7441c2cf989cf0
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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