Indolizine-1,3-dicarboxylic acid 1-benzyl ester → 3-Isocyanato-indolizine-1-carboxylic acid benzyl ester

HRID 1527197Notes

Reaction equation

HRID 1527197 reaction equation
[CH2:1]([O:8][C:9]([C:11]1[CH:12]=[C:13](C(O)=O)[N:14]2[C:19]=1[CH:18]=[CH:17][CH:16]=[CH:15]2)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(OC1C=C2C(=CC=1)[N:32]([C:36](N)=[O:37])C=C2N=C=O)C=C>>[CH2:1]([O:8][C:9]([C:11]1[CH:12]=[C:13]([N:32]=[C:36]=[O:37])[N:14]2[C:19]=1[CH:18]=[CH:17][CH:16]=[CH:15]2)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 68283859Indolizine-1,3-dicarboxylic acid 1-benzyl esterHCID 866737945-Allyloxy-3-isocyanato-indole-1-carboxylic acid amide

Product 1

HCID 866738133-Isocyanato-indolizine-1-carboxylic acid benzyl ester

Procedure

The title compound was prepared from indolizine-1,3-dicarboxylic acid 1-benzyl ester using the protocol described in step E scheme A4 for the preparation of 5-allyloxy-3-isocyanato-indole-1-carboxylic acid amide.

Sources & evidence

ORD record
ord-acdf7132f0974f72b02c9dd73965ec50
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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