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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1527229Generated: November 4, 2026

6-Chloroindole → (3-Acetyl-6-chloro-indol-1-yl)-acetic acid

https://huagongshe.com/reaction/1527229

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-ChloroindoleHCID 87111—
Reactant(3-Acetyl-5-trifluoromethoxy-indol-1-yl)acetic acidHCID 68284505—
Product(3-Acetyl-6-chloro-indol-1-yl)-acetic acidHCID 68284278—

Reaction Steps

was prepared from 6-chloro-1H-indole in a similar manner as described in Scheme A13 for the preparation of (3-acetyl-5-trifluoromethoxy-indol-1-yl)-acetic acid. Brown solid. MS: 252 [M+H]+, 274 [M+Na]+; tR (HPLC conditions k): 2.89 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09085555B2
Source datasetuspto-grants-2015_07
ORD IDord-8e140a34499549638e1a75b75c1a4514
Source noteuspto-grants-2015_07