HCID 68283534, compound → HCID 71009375, compound

HRID 1527236Notes

Reaction equation

HRID 1527236 reaction equation
[CH3:1][O:2][C:3](=[O:17])[CH2:4][C:5]1[CH:13]=[C:12]2[C:8]([C:9]([C:14](=[O:16])[CH3:15])=[CH:10][NH:11]2)=[CH:7][CH:6]=1.C(C1C2C(=CC=C(OC(F)(F)F)C=2)N([CH2:35][C:36]([OH:38])=[O:37])C=1)(=O)C>>[C:14]([C:9]1[C:8]2[C:12](=[CH:13][C:5]([CH2:4][C:3]([O:2][CH3:1])=[O:17])=[CH:6][CH:7]=2)[N:11]([CH2:35][C:36]([OH:38])=[O:37])[CH:10]=1)(=[O:16])[CH3:15]

Participants

3

Reactant 2

HCID 68283534HCID 68283534, compoundHCID 68284505(3-Acetyl-5-trifluoromethoxy-indol-1-yl)acetic acid

Product 1

HCID 71009375HCID 71009375, compound

Procedure

was prepared from (3-acetyl-1H-indol-6-yl)-acetic acid methyl ester in a similar manner as described in Scheme A13 for the preparation of (3-acetyl-5-trifluoromethoxy-indol-1-yl)-acetic acid. Brown solid. MS: 290 [M+H]+; tR (HPLC conditions k): 2.83 min.

Workup

  1. custom2.83 min.

Sources & evidence

ORD record
ord-03829637c90a446eaa6eed64f54cdb5f
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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