1H-Pyrrolo[2,3-c]pyridine-1-acetic acid, 3-acetyl- → HCID 71009486, compound

HRID 1527252Notes

Reaction equation

HRID 1527252 reaction equation
[C:1]([C:4]1[C:12]2[C:7](=C[N:9]=[CH:10][CH:11]=2)[N:6]([CH2:13][C:14]([OH:16])=[O:15])[CH:5]=1)(=[O:3])[CH3:2].[N:17]1C2NC=C(C(=O)C)C=2C=CN=1>>[C:1]([C:4]1[C:12]2[CH:11]=[CH:10][N:9]=[N:17][C:7]=2[N:6]([CH2:13][C:14]([OH:16])=[O:15])[CH:5]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 682831851H-Pyrrolo[2,3-c]pyridine-1-acetic acid, 3-acetyl-HCID 866738151-(7H-Pyrrolo[2,3-c]pyridazin-5-yl)ethanone

Product 1

HCID 71009486HCID 71009486, compound

Procedure

was prepared using similar procedures as described for the synthesis of (3-acetyl-pyrrolo[2,3-c]pyridin-1-yl)-acetic acid in Scheme A15 from 1-(7H-pyrrolo[2,3-c]pyridazin-5-yl)-ethanone (prepared according to J. Org. Chem. 2002, 67, 6226). MS (UPLC/MS): 220.1 [M+H]+, 178.0 [MH-CH3CO]+, 218.1 [M−H]−, 437.2 [2M−H]−.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-88670043bc954c8091a9bdfe5a6f38db
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

Loading…