1H-Pyrazolo[3,4-c]pyridine-1-acetic acid, 3-(aminocarbonyl)- → (3-Carbamoyl-7-methyl-pyrazolo[3,4-c]pyridin-1-yl)-acetic acid

HRID 1527294Notes

Reaction equation

HRID 1527294 reaction equation
[C:1]([C:4]1[C:12]2[C:7](=[CH:8][N:9]=[CH:10][CH:11]=2)[N:6]([CH2:13][C:14]([OH:16])=[O:15])[N:5]=1)(=[O:3])[NH2:2].[CH3:17]C1N=CC=C2C=NNC=12>>[C:1]([C:4]1[C:12]2[C:7](=[C:8]([CH3:17])[N:9]=[CH:10][CH:11]=2)[N:6]([CH2:13][C:14]([OH:16])=[O:15])[N:5]=1)(=[O:3])[NH2:2]

Participants

3

Reactant 2

HCID 682831141H-Pyrazolo[3,4-c]pyridine-1-acetic acid, 3-(aminocarbonyl)-HCID 682837107-methyl-1H-pyrazolo[3,4-c]pyridine

Product 1

HCID 71009416(3-Carbamoyl-7-methyl-pyrazolo[3,4-c]pyridin-1-yl)-acetic acid

Procedure

was prepared using the same procedure as for the preparation of 2-(3-carbamoyl-1H-pyrazolo[3,4-c]pyridin-1-yl)acetic acid starting from 7-methyl-1H-pyrazolo[3,4-c]pyridine (Scheme A26). MS (LC-MS): 235 [M+H]+, tR (HPLC conditions k): 0.6 min.

Workup

  1. customwas prepared
  2. custom0.6 min.

Sources & evidence

ORD record
ord-666982f1dd3d45debd91d6c65be0058a
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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