6-Methyl-1H-pyrazolo[4,3-c]pyridine → (3-Carbamoyl-6-methyl-pyrazolo[4,3-c]pyridin-1-yl)-acetic acid

HRID 1527311Notes

Reaction equation

HRID 1527311 reaction equation
CC1[N:7]=[CH:6][C:5]2C=NNC=2C=1.[C:11]([C:14]1[C:22]2[C:17](=[CH:18]N=C(C)[CH:21]=2)[N:16]([CH2:24][C:25]([OH:27])=[O:26])[N:15]=1)(=[O:13])[NH2:12]>>[C:11]([C:14]1[C:22]2[CH:21]=[N:7][C:6]([CH3:5])=[CH:18][C:17]=2[N:16]([CH2:24][C:25]([OH:27])=[O:26])[N:15]=1)(=[O:13])[NH2:12]

Participants

3

Reactant 2

HCID 213005706-Methyl-1H-pyrazolo[4,3-c]pyridineHCID 68283471HCID 68283471, compound

Product 1

HCID 71009484(3-Carbamoyl-6-methyl-pyrazolo[4,3-c]pyridin-1-yl)-acetic acid

Procedure

was prepared from 6-methyl-1H-pyrazolo[4,3-c]pyridine by using the same procedures as for the preparation of (3-carbamoyl-5-methyl-pyrazolo[3,4-c]pyridin-1-yl)-acetic acid (Scheme A27). MS (LC-MS): 235 [M+H]+, tR (HPLC conditions k): 0.29 min.

Workup

  1. custom0.29 min.

Sources & evidence

ORD record
ord-044f1da723154846ae748f04aa24d4d4
Source dataset
uspto-grants-2015_07
Patent number
US09085555B2

Reaction notes

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