HCID 86673872, compound → HCID 68284070, compound

Participants

Reaction Steps

A solution of 3-{2-[(2S,4S)-4-azido-2-(3-chloro-2-fluoro-benzylcarbamoyl)-pyrrolidin-1-yl]-2-oxo-ethyl}-indole-1-carboxylic acid amide (80 mg, 0.161 mmol) in MeOH (8 mL) was hydrogenated over Pd/C 10% (8 mg, 10% w/w) at RT (1 atm). The reaction mixture was filtered through a 0.45 microns filter and concentrated under reduced pressure to give the title compound as colorless foam. MS (LC/MS): 472 [M+H]+; tR (HPLC conditions b) 2.94 min.

Provenance & Evidence