3-Pyridinemethanamine → 4-methyl-2-(3-((3-methyl-5-phenylisoxazol-4-yl)methyl)-2-oxoimidazolidin-1-yl)-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide

HRID 152758Notes

Reaction equation

HRID 152758 reaction equation
[CH3:27][c:28]1[n:29][c:30]([N:36]2[C:37](=[O:54])[N:38]([CH2:41][c:42]3[c:43]([CH3:53])[n:44][o:45][c:46]3-[c:47]3[cH:48][cH:49][cH:50][cH:51][cH:52]3)[CH2:39][CH2:40]2)[s:31][c:32]1[C:33](=[O:34])[OH:35].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[s:6][cH:7][c:8]([CH2:9][N:10]3[CH2:11][CH2:12][N:13]([c:14]4[s:15][c:16]([C:17]([OH:18])=[O:19])[c:20]([CH3:21])[n:22]4)[C:23]3=[O:24])[c:25]2[cH:26]1.[NH2:55][CH2:56][c:57]1[cH:58][n:59][cH:60][cH:61][cH:62]1>>[CH3:27][c:28]1[n:29][c:30]([N:36]2[C:37](=[O:54])[N:38]([CH2:41][c:42]3[c:43]([CH3:53])[n:44][o:45][c:46]3-[c:47]3[cH:48][cH:49][cH:50][cH:51][cH:52]3)[CH2:39][CH2:40]2)[s:31][c:32]1[C:33](=[O:34])[NH:55][CH2:56][c:57]1[cH:58][n:59][cH:60][cH:61][cH:62]1

Participants

4

Reactant 3

HCID 310183-PyridinemethanamineHCID 580315052-(3-((5-Chlorobenzo[b]thiophen-3-yl)methyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylic acidHCID 580315224-Methyl-2-(3-((3-methyl-5-phenylisoxazol-4-yl)methyl)-2-oxoimidazolidin-1-yl)thiazole-5-carboxylic acid

Product 1

HCID 594812654-methyl-2-(3-((3-methyl-5-phenylisoxazol-4-yl)methyl)-2-oxoimidazolidin-1-yl)-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide

Sources & evidence

ORD record
ord-158f4638f02b4cf69cea31e7c20d350b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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