2,3,4,5-Tetramethoxy-6-methylbenzaldehyde → HCID 46180238, compound

HRID 1527660Notes

Reaction equation

HRID 1527660 reaction equation
[CH3:1][C:2]1[C:7]([CH:8]=O)=[C:6]([O:10][CH3:11])[C:5]([O:12][CH3:13])=[C:4]([O:14][CH3:15])[C:3]=1[O:16][CH3:17].CC1[C:24](/[CH:25]=[CH:26]/[C:27]([O:29][CH2:30][CH3:31])=[O:28])=[C:23](OC)C(OC)=C(OC)C=1OC>>[CH3:1][C:2]1[C:7](/[CH:8]=[C:26](\[CH2:25][CH2:24][CH3:23])/[C:27]([O:29][CH2:30][CH3:31])=[O:28])=[C:6]([O:10][CH3:11])[C:5]([O:12][CH3:13])=[C:4]([O:14][CH3:15])[C:3]=1[O:16][CH3:17]

Participants

3

Reactant 2

HCID 148523342,3,4,5-Tetramethoxy-6-methylbenzaldehydeHCID 46180172HCID 46180172, compound

Product 1

HCID 46180238HCID 46180238, compound

Procedure

Compound 8d was prepared from 7 (0.437 g, 1.82 mmol) as described above for 8a to give 0.275 g (0.780 mmol, 43%) of the product as a colorless oil following flash chromatography (1:3 EtOAc:hexanes).

Sources & evidence

ORD record
ord-1b239e6aa97c49b8a85d8c64d7bfaf13
Source dataset
uspto-grants-2015_07
Patent number
US09089605B2

Reaction notes

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