HCID 46180240, compound → HCID 46180241, compound

HRID 1527662Notes

Reaction equation

HRID 1527662 reaction equation
[CH3:1][C:2]1[C:7](/[CH:8]=[C:9](\[CH2:15][CH2:16][CH2:17][CH3:18])/[C:10]([O:12]CC)=[O:11])=[C:6]([O:19][CH3:20])[C:5]([O:21][CH3:22])=[C:4]([O:23][CH3:24])[C:3]=1[O:25][CH3:26]>CCOCC>[CH3:1][C:2]1[C:7](/[CH:8]=[C:9](\[CH2:15][CH2:16][CH2:17][CH3:18])/[C:10]([OH:12])=[O:11])=[C:6]([O:19][CH3:20])[C:5]([O:21][CH3:22])=[C:4]([O:23][CH3:24])[C:3]=1[O:25][CH3:26]

Participants

3

Reactant 1

HCID 46180240HCID 46180240, compound

Product 1

HCID 46180241HCID 46180241, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Compound 9e was prepared from 8e (0.166 g, 0.453 mmol) as described above for 9a using Method B to give 0.144 g (0.426 mmol, 94%) of the product as a yellow amorphous solid following flash chromatography (2:3 Et2O:hexanes 0.5% AcOH) and recrystallization from Et2O/hexanes.

Workup

  1. customto give

Sources & evidence

ORD record
ord-513d315d53f7474a8cf8a20166c5f885
Source dataset
uspto-grants-2015_07
Patent number
US09089605B2

Reaction notes

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