HCID 46180241, compound → HCID 25235421, compound

HRID 1527666Notes

Reaction equation

HRID 1527666 reaction equation
[CH3:1][C:2]1[C:7](/[CH:8]=[C:9](\[CH2:13][CH2:14][CH2:15][CH3:16])/[C:10]([OH:12])=[O:11])=[C:6]([O:17]C)[C:5]([O:19][CH3:20])=[C:4]([O:21][CH3:22])[C:3]=1[O:23]C>CCOCC>[CH3:22][O:21][C:4]1[C:3](=[O:23])[C:2]([CH3:1])=[C:7](/[CH:8]=[C:9](\[CH2:13][CH2:14][CH2:15][CH3:16])/[C:10]([OH:12])=[O:11])[C:6](=[O:17])[C:5]=1[O:19][CH3:20]

Participants

3

Reactant 1

HCID 46180241HCID 46180241, compound

Product 1

HCID 25235421HCID 25235421, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

Compound 10e was prepared from 9e (0.015 g, 0.044 mmol) as described above for 10a to give 0.005 g (0.018 mmol, 40%) of the product as a red solid following flash chromatography (1:1 Et2O:hexanes 0.5% AcOH) and recrystallization from Et2O/hexanes.

Workup

  1. customto give

Sources & evidence

ORD record
ord-1c7e5adf202f4631ae99e4488aebcbcd
Source dataset
uspto-grants-2015_07
Patent number
US09089605B2

Reaction notes

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