1,4-Dimethoxy-3-methylnaphthalene-2-carbaldehyde → HCID 46180045, compound

HRID 1527677Notes

Reaction equation

HRID 1527677 reaction equation
[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([O:13][CH3:14])=[C:5]([CH3:15])[C:4]=1[CH:16]=O.COC1C2C(=CC=CC=2)C(OC)=CC=1/[CH:32]=[C:33](\C)/[C:34]([O:36][CH2:37][CH3:38])=[O:35]>>[CH3:1][O:2][C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6]([O:13][CH3:14])=[C:5]([CH3:15])[C:4]=1/[CH:16]=[C:33](\[CH3:32])/[C:34]([O:36][CH2:37][CH3:38])=[O:35]

Participants

3

Reactant 2

HCID 128475291,4-Dimethoxy-3-methylnaphthalene-2-carbaldehydeHCID 46180044HCID 46180044, compound

Product 1

HCID 46180045HCID 46180045, compound

Procedure

Compound 98a was prepared from 34 (0.506 g, 2.20 mmol) as described above for 28a to give 0.541 g (1.42 mmol, 65%) of the product as a colorless oil following flash chromatography (1:19 i-Pr2O:hexanes).

Sources & evidence

ORD record
ord-1b71f95aec4e48a780466cdd70c55fa7
Source dataset
uspto-grants-2015_07
Patent number
US09089605B2

Reaction notes

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