HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diisopropyl Ether → Ethyl (E)-3-(3-bromo-1,4-dimethoxynaphthalen-2-yl)-2-methylpropenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diisopropyl Ether | HCID 7914 | — |
| Reactant | 3-Bromo-1,4-dimethoxy-2-naphthaldehyde | HCID 11208648 | — |
| Reactant | HCID 46180044 | HCID 46180044 | — |
| Product | Ethyl (E)-3-(3-bromo-1,4-dimethoxynaphthalen-2-yl)-2-methylpropenoate | HCID 46180107 | — |
Reaction Steps
Compound 98e was prepared from 38 (0.515 g, 1.75 mmol) as described above for 28a to give 0.373 g (0.984 mmol, 56%) of the product as a white solid following flash chromatography (1:19 i-Pr2O:hexanes) and recrystallization from Et2O/hexanes. (0.314 g E; 0.059 g Z)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09089605B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-83b9d314dd2e449789ab4e0d94cfa6b4 |
| Source note | uspto-grants-2015_07 |