HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dimethoxy-3-methylsulfanyl-2-naphthaldehyde → Ethyl (E)-3-(1,4-dimethoxy-3-methylsulfanylnaphthalen-2-yl)-2-methylpropenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dimethoxy-3-methylsulfanyl-2-naphthaldehyde | HCID 46180042 | — |
| Reactant | HCID 46180044 | HCID 46180044 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | Ethyl (E)-3-(1,4-dimethoxy-3-methylsulfanylnaphthalen-2-yl)-2-methylpropenoate | HCID 46180104 | — |
Reaction Steps
Compound 98h was prepared from 57 (0.308 g, 1.17 mmol) as described above for 28a to give 0.231 g (0.667 mmol, 55%) of the product as an amorphous yellow solid following flash chromatography (1:9 EtOAc:hexanes) and recrystallization from Et2O/hexanes. (0.165 g E; 0.065 g E/Z)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09089605B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-752de8d8133540cfb57a600cbfdb4a40 |
| Source note | uspto-grants-2015_07 |