HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → Ethyl (2R/S)-3-(3-bromo-1,4-dimethoxynaphthalen-2-yl)-2-methylpropionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 2-Bromo-3-bromomethyl-1,4-dimethoxynaphthalene | HCID 10406194 | — |
| Reactant | Ethyl 3-(3-bromo-1,4-dimethoxynaphthalen-2-yl)-propionate | HCID 46179963 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Ethyl (2R/S)-3-(3-bromo-1,4-dimethoxynaphthalen-2-yl)-2-methylpropionate | HCID 70835186 | — |
Reaction Steps
Compound 67b was prepared from 36 (0.244 g, 0.678 mmol) as described above for 67a to give 0.258 g (0.678 mmol, 100%) of the product as a EtOAc following flash chromatography (1:1 to 3:1 CH2Cl2:hexanes).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09089605B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-142b015b2b4a4935b00eeccb9fe03777 |
| Source note | uspto-grants-2015_07 |