HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-{5-[2-chloro-5-(trifluoromethyl)phenyl]pyrazin-2-yl}-2,6-difluorobenzamide → N-[5-(2-Chloro-5-trifluoromethyl-phenyl)-pyrazin-2-yl]-3-methyl-isonicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-{5-[2-chloro-5-(trifluoromethyl)phenyl]pyrazin-2-yl}-2,6-difluorobenzamide | HCID 11546102 | — |
| Reactant | 3-Methylpyridine-4-carbonyl chloride | HCID 13285864 | — |
| Product | N-[5-(2-Chloro-5-trifluoromethyl-phenyl)-pyrazin-2-yl]-3-methyl-isonicotinamide | HCID 11531284 | — |
Reaction Steps
Compound 3 was prepared in an analogous fashion to Compound 1 except that 3-methyl-isonicotinoyl chloride was used instead of 2,6-difluoro-benzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090570B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-792c0c6239ef434b826fbd5f47494a38 |
| Source note | uspto-grants-2015_07 |