HCID 68008520, compound → HCID 45788797, compound

HRID 1528111Notes

Reaction equation

HRID 1528111 reaction equation
[O:1]1[CH2:6][CH:5]=[C:4]([C:7]2[CH:8]=[CH:9][C:10]([NH2:13])=[N:11][CH:12]=2)[CH2:3][CH2:2]1>C(O)C>[O:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:8]=[CH:9][C:10]([NH2:13])=[N:11][CH:12]=2)[CH2:3][CH2:2]1

Participants

3

Reactant 1

HCID 68008520HCID 68008520, compound

Product 1

HCID 45788797HCID 45788797, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The title compound was prepared as described in example 61, substituting tert-butyl-6-[3-(8-fluoro-quinolin-4-yl)-ureido]-3′,6′-dihydro-2′H-[2,4′]bipyridinyl-1′-carboxylate by 5-(3,6-dihydro-2H-pyran-4-yl)pyridin-2-amine and by using ethanol as solvent.

Sources & evidence

ORD record
ord-f94043f65e6b4aa3a3e0e7fd8a48b6de
Source dataset
uspto-grants-2015_07
Patent number
US09090592B2

Reaction notes

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