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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528197Generated: November 4, 2026

6-Chloro-3-nitropyridin-2(1H)-one → 3-Amino-6-chloro-pyridin-2-ol

https://huagongshe.com/reaction/1528197

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-3-nitropyridin-2(1H)-oneHCID 2328516—
ReactantHCID 178425501HCID 178425501—
Product3-Amino-6-chloro-pyridin-2-olHCID 79003732—

Reaction Steps

In a manner analogous to EXAMPLE 1 (steps 1 to 3, 6 and 7), 3-(6-chloro-2-hydroxypyridin-3-ylamino)-4-{[(5-methylfuran-2-yl)-(3-methyloxetan-3-yl)methyl]amino}cyclobut-3-ene-1,2-dione was prepared from 6-chloro-3-nitro-1H-pyridin-2-one. HPLC 94.8%, ES− [402].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090596B2
Source datasetuspto-grants-2015_07
ORD IDord-28f6e12974cd473aab2d54baa2f61156
Source noteuspto-grants-2015_07