HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenylboronic acid → 5-(4-Cyanophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenylboronic acid | HCID 2734326 | — |
| Reactant | 5-Bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid | HCID 58192592 | — |
| Product | 5-(4-Cyanophenyl)-6-(2,2,2-trifluoroethoxy)nicotinic acid | HCID 66678700 | — |
Reaction Steps
The title compound was synthesized in analogy to Example BQ using 5-bromo-6-(2,2,2-trifluoroethoxy)-3-pyridinecarboxylic acid (CAN 1211586-75-2) and B-(4-cyanophenyl)-boronic acid, (CAN 126747-14-6) as starting materials; MS (ESI): 321.2 (M−H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09090599B2 |
| Source dataset | uspto-grants-2015_07 |
| ORD ID | ord-5bb2a9883460422292870799b8d388c8 |
| Source note | uspto-grants-2015_07 |