1017785-44-2 → HCID 56928481, compound

HRID 1528430Notes

Reaction equation

HRID 1528430 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([O:17][CH2:18][C:19]([F:22])([F:21])[F:20])=[N:10][CH:11]=[C:12]([CH:16]=2)[C:13](O)=[O:14])=[CH:4][CH:3]=1.[Cl:23][C:24]1[C:25]([CH2:30][NH2:31])=[N:26][N:27]([CH3:29])[CH:28]=1>>[Cl:23][C:24]1[C:25]([CH2:30][NH:31][C:13](=[O:14])[C:12]2[CH:16]=[C:8]([C:5]3[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=3)[C:9]([O:17][CH2:18][C:19]([F:22])([F:21])[F:20])=[N:10][CH:11]=2)=[N:26][N:27]([CH3:29])[CH:28]=1

Participants

3

Reactant 2

HCID 252523881017785-44-2HCID 666869715-(4-Chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid

Product 1

HCID 56928481HCID 56928481, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-(4-chloro-phenyl)-6-(2,2,2-trifluoro-ethoxy)-nicotinic acid (CAS Registry No. 1018782-82-5) and [(4-chloro-1-methyl-1H-pyrazol-3-yl)methyl]amine (CAS Registry No. 1017785-44-2) as starting materials; LC-MS (UV peak area/ESI) 100%, 458.0604 (M+H)+.

Sources & evidence

ORD record
ord-59d946e0dda946d7b7b247a16443d1d7
Source dataset
uspto-grants-2015_07
Patent number
US09090599B2

Reaction notes

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