HCID 17604995, compound → HCID 56928691, compound

HRID 1528442Notes

Reaction equation

HRID 1528442 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:13]([O:14][CH2:15][C:16]([F:19])([F:18])[F:17])=[CH:12][N:11]=[C:10]([C:20](O)=[O:21])[CH:9]=2)=[CH:4][CH:3]=1.[CH3:23][CH:24]([C:26]1[O:30][N:29]=[C:28]([CH2:31][NH2:32])[N:27]=1)[CH3:25]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[C:13]([O:14][CH2:15][C:16]([F:18])([F:17])[F:19])=[CH:12][N:11]=[C:10]([C:20]([NH:32][CH2:31][C:28]3[N:27]=[C:26]([CH:24]([CH3:25])[CH3:23])[O:30][N:29]=3)=[O:21])[CH:9]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 17604995HCID 17604995, compoundHCID 66687043HCID 66687043, compound

Product 1

HCID 56928691HCID 56928691, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 4-(4-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (example D) and 5-(1-methylethyl)-1,2,4-oxadiazole-3-methanamine, (CAN 936940-30-6) as starting materials; LC-MS (UV peak area/ESI) 100%, 455.1092 (M+H)+.

Sources & evidence

ORD record
ord-ec1d98c5c9de4d0cb56fe3d941e80a55
Source dataset
uspto-grants-2015_07
Patent number
US09090599B2

Reaction notes

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