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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1528448Generated: November 2, 2026

HCID 66687043, compound → 4-(4-chlorophenyl)-5-(2,2,2-trifluoroethoxy)-N-((5-(trifluoromethyl)isoxazol-3-yl)methyl)picolinamide

https://huagongshe.com/reaction/1528448

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66687043HCID 66687043—
Reactant(5-(Trifluoromethyl)-1,2-oxazol-3-yl)methanamine hydrochlorideHCID 66687333—
Product4-(4-chlorophenyl)-5-(2,2,2-trifluoroethoxy)-N-((5-(trifluoromethyl)isoxazol-3-yl)methyl)picolinamideHCID 56928796—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 4-(4-chloro-phenyl)-5-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (example D) and 5-trifluoromethyl-isoxazol-3-methanamine hydrochloride (example BG) as starting materials; LC-MS (UV peak area/ESI) 100%, 480.0532 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09090599B2
Source datasetuspto-grants-2015_07
ORD IDord-bcbb50c79c7e445aa0f27bbecd006a0f
Source noteuspto-grants-2015_07